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Onset at an early age, pruritus and excoriation, chronic or chronic relapsing course for more than 6 weeks, age-related eczematous morphology and distribution, as well as a positive family history for atopic diseases (allergic bronchial asthma, allergic rhinitis and conjunctivitis or atopic eczema), form the most striking criteria

(PubMed) Zempleni J, Trusty TA, Mock DM